{"id":1396,"date":"2019-02-26T20:39:17","date_gmt":"2019-02-27T02:39:17","guid":{"rendered":"https:\/\/www.crpa-acrp-bulletin.ca\/?p=1396"},"modified":"2020-05-19T08:33:51","modified_gmt":"2020-05-19T14:33:51","slug":"health-canada-and-the-canadian-nuclear-safety-commission-partners-in-low-dose-radiation-research-in-canada-and-abroad","status":"publish","type":"post","link":"https:\/\/www.crpa-acrp-bulletin.ca\/fr\/2019\/02\/26\/health-canada-and-the-canadian-nuclear-safety-commission-partners-in-low-dose-radiation-research-in-canada-and-abroad\/","title":{"rendered":"Health Canada and the Canadian Nuclear Safety Commission: Partners in Low-Dose-Radiation Research in Canada and Abroad"},"content":{"rendered":"<div class='content-column one_third'><div style=\"padding-right:10px;\"><div style=\"padding: 8px 5px 5px 5px; background-color: #eeeeee; border: #dddddd 2px solid;\">\n<h4>R\u00e9sum\u00e9<\/h4>\n<p>En 2018, des membres du personnel de la Commission canadienne de s\u00fbret\u00e9 nucl\u00e9aire et de Sant\u00e9 Canada ont particip\u00e9 \u00e0 plusieurs ateliers et congr\u00e8s internationaux portant sur la recherche sur le rayonnement \u00e0 faible dose (&lt;\u00a0100\u00a0mSv). L\u2019int\u00e9r\u00eat pour la recherche sur le rayonnement \u00e0 faible dose ne cesse de cro\u00eetre au Canada et ailleurs dans le monde. En r\u00e9ponse, les deux organismes priorisent la recherche sur le rayonnement \u00e0 faible dose et encouragent le Gouvernement du Canada \u00e0 renforcer leurs liens avec la communaut\u00e9 internationale des chercheurs en rayonnement. L\u2019objectif commun est d\u2019am\u00e9liorer la coordination et la collaboration internationales, en plus de rendre la recherche sur le rayonnement encore plus efficace.<\/p>\n<\/div><\/div><\/div>\n<div class='content-column two_third last_column'><div style=\"padding-left:10px;\"><p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1400\" src=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Charlotte-e1551148624705.jpg\" alt=\"\" width=\"1200\" height=\"651\" srcset=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Charlotte-e1551148624705.jpg 640w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Charlotte-e1551148624705-300x163.jpg 300w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Charlotte-e1551148624705-520x282.jpg 520w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><span style=\"font-size: 85%;\">Canadian Nuclear Safety Commission (CNSC) and Health Canada (HC) staff at the International Dose Effect Alliance 2018 meeting in Charlotte, NC.<\/span><\/p>\n<p>The year 2018 saw both the Canadian Nuclear Safety Commission (CNSC) and Health Canada (HC) staff participate in several international workshops and conferences on the subject of low-dose-radiation research (LDRR). (See Table 1.)<\/p>\n<p><strong>Table 1: <\/strong>Key international workshops and conferences in 2018<\/p>\n<table>\n<thead>\n<tr>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>Event<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>Scoping meeting for global coordination of low-dose-radiation research<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>European Radiological Protection Research <\/strong><br \/>\n<strong>Week 2018<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>International Dose Effect Alliance 2018<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>Hosts<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Organisation for Economic Co-operation and Development Nuclear Energy Agency<\/li>\n<li>Universit\u00e0 degli studi di Milano<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Multidisciplinary European Low Dose Initiative<\/li>\n<li>Institute for Medical Research and Occupational Health, Croatia<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Electric Power Research Institute, Charlotte, NC<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>Canadian Government Participants<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Health Canada<\/li>\n<li>Canadian Nuclear Safety Commission<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Canadian Nuclear Safety Commission<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Health Canada<\/li>\n<li>Canadian Nuclear Safety Commission<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\"><strong>Primary Goals<\/strong><\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Discuss the needs for and approaches to global coordination of low-dose-radiation research<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Learn about the different European research platforms and express interest in membership in the Multidisciplinary European Low Dose Initiative<\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 25%; vertical-align: top; text-align: left;\">\n<ul>\n<li>Exchange information on programs, priorities, strategic research agendas, and results<\/li>\n<li>Share an overview of the federal low-dose-radiation research program<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>LDRR (&lt; 100 mSv) is key to fulfilling parts of both HC\u2019s (Radiation Protection Bureau and Consumer and Clinical Radiation Protection Bureau) and CNSC\u2019s mandates, which include protecting Canadians from the health risks of exposure to ionizing radiation.<\/p>\n<p>Lifetime doses below 100 mSv are especially relevant to nuclear energy workers. Low doses from nuclear facilities, which are approximately 100 to 1,000 times lower than the CNSC public dose limit (1 mSv\/year),[<a href=\"#a1\">1<\/a>] are also relevant to members of the public.<\/p>\n<p>The Government of Canada continues to invest in and conduct LDRR to contribute to the body of evidence that informs the International Framework for Radiation Safety. In turn, this informs the application and incorporation of international recommendations into Canadian regulations and national guidance.<\/p>\n<p>The International Framework for Radiation Safety is partly based on the linear no-threshold (LNT) model. The LNT model is a dose-response model that describes a direct and proportional relationship between radiation exposure and cancer risk\u2014where low-dose-radiation risk is extrapolated from moderate- to high-dose data (&gt; 100 mSv). Thus, to better inform risk assessment at low doses, LDRR seeks to provide scientific evidence to reduce the statistical uncertainties at low doses.<\/p>\n<p>Interest and activity in LDRR is continuing to grow in Canada and around the world. In response, CNSC and HC are directing researchers and resources towards low-dose-research priorities. It is essential that the Government of Canada stay informed of current research activities and form stronger ties with the international radiation research community. Improving international coordination and collaboration, and thus the effectiveness of radiation research, is a goal shared by HC, CNSC, and the international community.<\/p>\n<p>The advantages of collaborating on and coordinating LDRR on a national and\/or international level include:<\/p>\n<ul>\n<li>Saving on research costs<\/li>\n<li>Making better use of existing research infrastructure<\/li>\n<li>Improving access to and leveraging external expertise<\/li>\n<li>Broadening the international profile of Canadian scientists and their research laboratories<\/li>\n<li>Demonstrating Canadian leadership to the international radiation protection community<\/li>\n<li>Focusing the research program<\/li>\n<\/ul>\n<h1>International coordination<\/h1>\n<p>In September, HC, CNSC staff, and other Canadian representatives participated in the Organisation for Economic Co-operation and Development (OECD) Nuclear Energy Agency (NEA) scoping meeting for global coordination of LDRR held at the University of Milan. (See Table 1.) The meeting brought together 35 participants from 13 countries, including European radiological protection research platforms, regulatory authorities, and research organizations. Given the amount of low-dose research being conducted and continuing in the world, and its importance, those in attendance expressed interest in some level of global coordination.<\/p>\n<p>Following are some of the topics discussed at the meeting:<\/p>\n<ul>\n<li>Ongoing and planned research<\/li>\n<li>Research collaboration and cooperation<\/li>\n<li>LDRR priorities<\/li>\n<li>Mechanisms to more effectively foster global research collaboration and cooperation<\/li>\n<li>Effects of stakeholder concerns on research priorities<\/li>\n<\/ul>\n<p>The result of these discussions led to the drafting of high-level recommendations for the NEA\u2019s Committee on Radiological Protection and Public Health (CRPPH) meeting to be held in March 2019. CRPPH is being encouraged to consider the following:<\/p>\n<ul>\n<li>Discussing the need for global coordination of low-dose research in an all-hazards context<\/li>\n<li>Creating a high-level group to design and carry out such global coordination<\/li>\n<li>Defining the benefits such an approach will bring to participating countries\/organizations<\/li>\n<\/ul>\n<h1>European coordination<\/h1>\n<p>CNSC staff attended the third <a href=\"https:\/\/erpw2018.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">European Radiological Protection Research Week (ERPW2018)<\/a> in Rovinj, Croatia. (See Table 1), hosted by the Multidisciplinary European Low Dose Initiative (MELODI) and the Institute for Medical Research and Occupational Health (IMROH). This annual event showcases radiation research conducted or funded by European research platforms:<\/p>\n<ul>\n<li>Multidisciplinary European Low Dose Initiative (MELODI)<\/li>\n<li>European Radioecology Alliance (ERA)<\/li>\n<li>European Radiation Dosimetry (EURADOS) Group<\/li>\n<li>European Platform on Preparedness for Nuclear and Radiological Emergency Response and Recovery (NERIS)<\/li>\n<li>European Alliance for Medical Radiation Protection Research (EURAMED)<\/li>\n<li>European Joint Programme for the Integration of Radiation Protection Research (CONCERT)<\/li>\n<\/ul>\n<p>At ERPW2018, CNSC staff attended the MELODI parallel sessions. Following are some of the topics discussed:<\/p>\n<ul>\n<li>The shape of the dose-response relationship for radiation-induced health effects<\/li>\n<li>Health effects of inhomogeneous dose distributions<\/li>\n<li>Radiation quality and internal emitters<\/li>\n<li>New findings in biological and health effects at low doses<\/li>\n<li>The role of genetic and epigenetic modifications in radiation-induced health effects<\/li>\n<\/ul>\n<p>ERPW provides an opportunity to develop personal networks within the radiation research community and connect with its stakeholders and to gain access to key information. Notably, CNSC staff were interested in learning more about proposed revisions to articles in MELODI\u2019s statutes, which were unanimously approved at its Extraordinary General Assembly. Among the revised statutes was a change that allows organizations from non-European countries to become members of MELODI. CNSC and HC staff are in discussions with MELODI about initiating membership applications for their respective organizations.<\/p>\n<div class='content-column one_half'><div style=\"padding-right:10px;\"><p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1402\" src=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Milan.jpg\" alt=\"\" width=\"480\" height=\"640\" srcset=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Milan.jpg 480w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Milan-225x300.jpg 225w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><br \/>\n<span style=\"font-size: 85%;\">Canadian Nuclear Safety Commission (CNSC) and Health Canada (HC) staff attending the Organisation for Economic Co-operation and Development Nuclear Energy Agency scoping meeting for global coordination of low-dose-radiation research in Milan, Italy.<\/span><\/p><\/div><\/div>\n<div class='content-column one_half last_column'><div style=\"padding-right:10px;\"><p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1403\" src=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Rovinj.jpeg\" alt=\"\" width=\"1518\" height=\"2024\" srcset=\"https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Rovinj.jpeg 1518w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Rovinj-225x300.jpeg 225w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Rovinj-768x1024.jpeg 768w, https:\/\/www.crpa-acrp-bulletin.ca\/wp-content\/uploads\/2019\/02\/CRPA-40-1-CNSC-photo-in-Rovinj-520x693.jpeg 520w\" sizes=\"auto, (max-width: 1518px) 100vw, 1518px\" \/><span style=\"font-size: 85%;\">Picturesque Rovinj, Croatia, host city for European Radiological Protection Research Week 2018.<\/span><\/p><\/div><\/div><div class='clear_column'><\/div>\n<h1>National coordination<\/h1>\n<p>While discussions are ongoing concerning global coordination of LDRR, similar discussions are being held in Canada about national coordination. Momentum is building to create a national framework that would include HC, CNSC, and other Canadian research organizations.<\/p>\n<p>HC and CNSC have taken the lead and are drafting terms of reference for a federal LDRR program. Our shared vision and priorities for the health and environmental protection themes under the Federal Nuclear Science and Technology Work Plan position us well to form the nucleus of a LDRR program. From this nucleus, the federal government program could expand to a national initiative that draws in other Canadian organizations to enhance collaboration and coordination.<\/p>\n<p>The foundation of the federal LDRR program will be independent and joint research led by HC and CNSC that addresses our core and shared priorities. The research will be defined through a roadmap that will incorporate the Adverse Outcome Pathways methodology[<a href=\"#a2\">2<\/a>] to coordinate research and focus resources.<\/p>\n<p>In December 2018, HC and CNSC presented an overview of the federal LDRR program for the first time on an international stage at the International Dose Effect Alliance (IDEA) workshop in Charlotte, NC, which was hosted by the Electric Power Research Institute (EPRI). (See Table 1.)<\/p>\n<h1>Conclusion<\/h1>\n<p>A federally led LDRR program will harmonize LDRR priorities across federal organizations and effectively leverage expertise and capacity. This will lay the foundation upon which we can build a national framework in anticipation of the international coordination and collaboration that are essential to building a successful program for Canada.<\/p>\n<p>The federal LDRR program will have the following objectives:<\/p>\n<ul>\n<li>Focus resources to identify and address common research priorities and knowledge gaps<\/li>\n<li>Increase sharing of expertise, samples, resources, facilities, and research findings<\/li>\n<li>Build new expertise through cross-training opportunities<\/li>\n<li>Leverage funding opportunities<\/li>\n<\/ul>\n<p>CNSC and HC are looking forward to 2019\u2014a year filled with new beginnings!<\/p>\n<div id=\"a1\"><\/div>\n<p>1.\u00a0 \u00a0 Lane, R., et al. 2013. Radiation Exposure and Cancer Incidence (1990 to 2008) around Nuclear Power Plants in Ontario, Canada. <em>Journal of Environmental Protection<\/em>. <em>4<\/em>(9).<\/p>\n<div id=\"a2\"><\/div>\n<p>2.\u00a0 \u00a0\u00a0<a href=\"http:\/\/www.oecd.org\/chemicalsafety\/testing\/adverse-outcome-pathways-molecular-screening-and-toxicogenomics.htm\" target=\"_blank\" rel=\"noopener noreferrer\">Adverse Outcome Pathways, Molecular Screening and Toxicogenomics<\/a>.<\/p>\n<div style=\"padding: 10px 10px 0 10px; background-color: #eeeeee; border: #dddddd 2px solid;\">\n<h2>Julie Leblanc<\/h2>\n<p>Julie Leblanc is a radiation and health sciences officer at the Canadian Nuclear Safety Commission. She also sits on the research subcommittee for Theme 1 of the Federal Nuclear Science and Technology Work Plan and on the program advisory committee for the CANDU Owners Group\u2019s low-dose program.<\/p>\n<p>Julie Leblanc est responsable de la science du rayonnement et de la sant\u00e9 \u00e0 la Commission canadienne de s\u00fbret\u00e9 nucl\u00e9aire. Elle si\u00e8ge \u00e9galement au sous-comit\u00e9 de recherche pour le premier th\u00e8me du Plan de travail f\u00e9d\u00e9ral sur les activit\u00e9s de science et technologie nucl\u00e9aires, ainsi qu\u2019au comit\u00e9 consultatif du programme de rayonnement \u00e0 faible dose du Groupe des propri\u00e9taires de CANDU (GPC).<\/p>\n<h2>Deepti Bijlani<\/h2>\n<p>Deepti Bijlani is a senior project manager at Health Canada. She is responsible for coordinating and leading the LDRR program activities at Health Canada.<\/p>\n<p>Deepti Bijlani est directrice de projet principale \u00e0 Sant\u00e9 Canada. Elle est responsable de la coordination et de la gestion des activit\u00e9s du programme de recherche sur le rayonnement \u00e0 faible dose de Sant\u00e9 Canada.<\/p>\n<\/div><\/div><\/div><div class='clear_column'><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The year 2018 saw both the Canadian Nuclear Safety Commission and Health Canada staff participate in several international workshops and conferences on the subject of low-dose-radiation research. \/ En 2018, des membres du personnel de la Commission canadienne de s\u00fbret\u00e9 nucl\u00e9aire et de Sant\u00e9 Canada ont particip\u00e9 \u00e0 plusieurs ateliers et congr\u00e8s internationaux portant sur la recherche sur le rayonnement \u00e0 faible dose.<\/p>\n","protected":false},"author":42,"featured_media":1433,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[3,2],"tags":[],"class_list":["post-1396","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-features"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Health Canada and the Canadian Nuclear Safety Commission: Partners in Low-Dose-Radiation Research in Canada and Abroad - CRPA-ACRP Bulletin<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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