{"id":7434,"date":"2026-02-11T12:25:00","date_gmt":"2026-02-11T18:25:00","guid":{"rendered":"https:\/\/www.crpa-acrp-bulletin.ca\/?p=7434"},"modified":"2026-02-11T12:25:00","modified_gmt":"2026-02-11T18:25:00","slug":"dosimetrie-par-fibre-optique-pour-la-protontherapie-faits-saillants-de-la-recherche-de-triumf","status":"publish","type":"post","link":"https:\/\/www.crpa-acrp-bulletin.ca\/fr\/2026\/02\/11\/dosimetrie-par-fibre-optique-pour-la-protontherapie-faits-saillants-de-la-recherche-de-triumf\/","title":{"rendered":"Dosim\u00e9trie par fibre optique pour la protonth\u00e9rapie : faits saillants de la recherche de TRIUMF"},"content":{"rendered":"

<\/a><\/p>\n

 <\/p>\n

Patient dosimetry is a critical aspect of radioprotection during external beam radiotherapy, and it plays an even more critical role in proton therapy, where tissue dose rate changes rapidly along the beam travel direction.<\/p>\n

TRIUMF, Canada\u2019s national accelerator laboratory, is the only facility in Canada to have operated a clinical proton therapy centre. Between 1995 and 2019, more than 200 patients with ocular melanomas (a rare form of cancer) were treated with external proton beams at TRIUMF. While clinical operations have stopped, TRIUMF has transformed its beamline into the TRIUMF Proton Therapy Research Centre (PTRC) and is continuing its proton-therapy-related research program, with a focus on real-time dosimetry at both conventional and ultra-high dose rates.[1]<\/a><\/p>\n

Proton therapy dosimetry is typically performed with ionization chambers and radiochromic films. However, both methods have some limitations. For example, ionization chambers have a limited resolution and radiochromic films cannot provide real-time information. Optical fibres have emerged as an attractive possibility for proton therapy dosimetry as they offer solutions to some of the limitations of dosimeters currently used in clinical practice. Additionally, they can operate in vacuum, as well as in vivo<\/em> environments, at extreme temperatures, and in the presence of large electric and magnetic fields.[2]<\/a><\/p>\n

In some fibre materials, exposure to radiation will induce the spontaneous emission of light in the visible spectrum, a phenomenon called radiation-induced luminescence (RIL). The material of the fibre core can be doped with certain elements, like cerium and nitrogen, to create more luminescent defect centres and increase the light yield under radiation.[3]<\/a> The light created in the section of fibre under irradiation is transported along the rest of the optical fibre to a photon detector located outside of the radiation field, where the light intensity is measured and used to calculate the dose and dose rate in the radiation field. The main challenge of these RIL systems is that a very high dose rate on the fibre is required to create a measurable amount of light. A related dosimeter concept is to couple scintillating material to the optical fibre. The tip of the fibre can be hollowed out and filled with scintillating material, or a small piece of scintillating material of matching size can be attached to the fibre tip. The fibre then acts as a light transport system to the photon counter.<\/p>\n

The ideal optical fibre system for proton therapy dosimetry should have a linear light yield response to dose over the whole clinically relevant range that is independent of dose rate and particle energy. The fibre material should be as near as possible to tissue-equivalent to reduce the need for corrections and calibrations. The fibres should also be as small as possible to maximise the spatial resolution.<\/p>\n

Recent results from the PTRC demonstrate, for example, that a multi-fibre sensor system can provide, in real-time, beam profile information that is in agreement with radiochromic film measurements of the same beam,[4]<\/a> as shown in Figure 1.<\/p>\n

\"\"

Figure 1: (a) Multi-fibre sensor prototype mounted on the 74 MeV beamline of the PTRC, (b) Beam profile for varying beam aperture size, measured with a multi-fibre array (points) and dosimetric film (lines). The intensity is normalized to 1 for both measurement methods at the highest measurement with the largest aperture.<\/p><\/div>\n

\"\"

Figure 2: Comparison of the scintillating fibre sensor response to proton-induced dose and neutron-induced dose for four scintillating materials.<\/p><\/div>\n

Optical fibres have also been exposed to the neutron beams available at TRIUMF. The difference in response of scintillating optical fibres to proton- and neutron-induced dose enables the design of a proton therapy patient dosimeter that can distinguish between the primary dose from the proton beam and the unavoidable but undesirable neutron dose to the patient that comes from the interaction of the proton beam with beamline elements and the patient\u2019s own non-cancerous tissues.[5]<\/a> The marked difference in response to proton- and neutron-induced dose between different scintillating materials studied at the PTRC is shown in Figure 2.<\/p>\n

As a former proton therapy clinical facility, TRIUMF\u2019s PTRC is an exceptional research asset for Canada, and the centre hosts both internal and external research teams interested in multiple topics related to proton therapy. The PTRC team is especially excited about the potential use of their research in improving patient safety during proton therapy treatments through high-precision real-time dosimetry.<\/p>\n

References<\/h2>\n

[1]<\/a> C. B\u00e9langer-Champagne et al.<\/em>, \u00ab\u00a0PIF & NIF: The Proton and Neutron Irradiation Facilities at TRIUMF.\u00a0\u00bb Nuclear Physics News<\/em>, vol. 34, no. 4 (2024): 25-30.<\/span><\/p>\n

[2]<\/a> S. O\u2019Keeffe, \u201cOptical Fibres for Radiation Dosimetry.\u201d In: Matias, I., Ikezawa, S., Corres, J. (eds) Fiber Optic Sensors. Smart Sensors, Measurement and Instrumentation<\/em><\/span>, vol 21. Springer (2017): 149-165.<\/span><\/p>\n

[3]<\/a> F. Fricano<\/span>\u00a0<\/span>et al<\/em>., \u00ab\u00a0Very High Dose Rate Proton Dosimetry with Radioluminescent Silica-Based Optical Fibers,\u00a0\u00bb<\/span>\u00a0<\/span>IEEE Transactions on Nuclear Science<\/em>, vol. 71, no. 8 (2024): 1829-1836.<\/span><\/p>\n

[4]<\/a> C. Penner <\/span><\/span>et al<\/em>., \u00ab\u00a0A Multi-Point Optical Fibre Sensor for Proton Therapy.\u00a0\u00bb Electronics<\/i>, vol. 13, no. 6 (2024): 1118.<\/span><\/span><\/p>\n

[5]<\/a>\u00a0J. Niedermeier <\/span><\/span>et al<\/em>.,\u00ab\u00a0Optical fibers as dosimeter detectors for mixed proton\/neutron fields\u2014A <\/span>biological dosimeter.\u00a0\u00bbElectronics<\/i> vol. 12, no. 2 (2023): 324.<\/span><\/span><\/p>\n

 <\/p>\n

\n

R\u00e9sum\u00e9<\/h2>\n
\n
TRIUMF, le laboratoire national du Canada dot\u00e9 d\u2019un acc\u00e9l\u00e9rateur, est la seule installation au Canada \u00e0 avoir exploit\u00e9 un centre de protonth\u00e9rapie<\/span><\/div>\n
clinique, traitant <\/span>plus de 200 patients avec des m\u00e9lanomes oculaires entre 1995 et 2019. Bien que les activit\u00e9s cliniques aient cess\u00e9, TRIUMF a transform\u00e9 sa ligne de faisceau qui est devenue le TRIUMF <\/span>Proton Therapy Research Centre (PTRC). Dans cet article, Camille B\u00e9langer-Champagne et Cornelia Hoehr expliquent ce qu\u2019est la dosim\u00e9trie pour la protonth\u00e9rapie et parlent des r\u00e9cents r\u00e9sultats du PTRC de TRIUMF.<\/span><\/div>\n<\/div>\n<\/div>\n

 <\/p>\n

\n

\"\"Camille B\u00e9langer-Champagne<\/h2>\n

Camille est une physicienne exp\u00e9rimentale chez TRIUMF. Elle coordonne les activit\u00e9s des installations d\u2019irradiation de proton et de neutron, o\u00f9 les composantes \u00e9lectroniques et les syst\u00e8mes, les capteurs et les autres mat\u00e9riaux sont soumis \u00e0 des essais de rayonnement.<\/p>\n<\/div>\n

 <\/p>\n

\n
\n

\"\"Cornelia Hoehr<\/h2>\n
Cornelia est la directrice de la division des sciences de la vie chez TRIUMF, chercheuse scientifique principale chez TRIUMF et professeure adjointe \u00e0 l\u2019Universit\u00e9 de Victoria et \u00e0 l\u2019universit\u00e9 de la Colombie-Britannique, Okanagan. Ses recherches portent sur les cibles pour la production de nouveaux isotopes m\u00e9dicaux et de nouvelles modalit\u00e9s pour le traitement du cancer.<\/span><\/div>\n<\/div>\n<\/div>\n

Vous voulez lire d\u2019autres articles comme celui-ci ?<\/h2>\n

Le\u00a0Bulletin<\/em> de l\u2019Association canadienne de la radioprotection (ACRP) est une publication essentielle \u00e0 tout professionnel de la radioprotection du Canada. Son contenu \u00e9ditorial procure aux professionnels de la radioprotection les enseignements, l\u2019information, les conseils et les solutions utiles, tous n\u00e9cessaires pour demeurer \u00e0 l\u2019avant-garde de la profession.<\/p>\n

Abonnez-vous aujourd\u2019hui pour que nous vous envoyions un courriel chaque fois qu\u2019un nouveau num\u00e9ro est mis en ligne. Revisitez souvent le site entre chaque num\u00e9ro pour obtenir les mises \u00e0 jour et consulter de nouveaux articles.<\/p>\n

Ne ratez aucun num\u00e9ro. Abonnez-vous d\u00e8s aujourd\u2019hui !<\/p>\nAbonnez-vous<\/span><\/a>\n","protected":false},"excerpt":{"rendered":"

TRIUMF, le laboratoire national du Canada dot\u00e9 d\u2019un acc\u00e9l\u00e9rateur, est la seule installation au Canada \u00e0 avoir exploit\u00e9 un centre de protonth\u00e9rapie clinique. Bien que les activit\u00e9s cliniques aient cess\u00e9, TRIUMF a transform\u00e9 sa ligne de faisceau qui est devenue le TRIUMF Proton Therapy Research Centre (PTRC). Poursuivez votre lecture pour en savoir plus sur le travail r\u00e9alis\u00e9 par cet \u00e9quipement de recherche exceptionnel pour le Canada!<\/p>\n","protected":false},"author":164,"featured_media":7426,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[29],"tags":[],"class_list":["post-7434","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles-fr"],"yoast_head":"\nDosim\u00e9trie par fibre optique pour la protonth\u00e9rapie : faits saillants de la recherche de TRIUMF - CRPA-ACRP Bulletin<\/title>\n<meta name=\"description\" content=\"Le laboratoire national du Canada dot\u00e9 d\u2019un acc\u00e9l\u00e9rateur a transform\u00e9 sa ligne de faisceau qui est devenue le TRIUMF Proton Therapy Research Centre (PTRC) qui est maintenant un \u00e9quipement de recherche exceptionnel pour le Canada!\" \/>\n<meta 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